Background Informed consent confers upon participants the right to decline or accept participation in a study in equal measure. Consent declines can be used as a potential metric to assess the adequacy of the informed consent process. Limited literature is available on the reporting of consent declines in Clinical Research. We evaluated randomized controlled trials published in three high-impact factor journals for consent declines to assess the extent of exertion of autonomy by research participants. Methods CONSORT flow charts in RCTs (...) published in New England Journal of Medicine, The Lancet and Journal of the American Medical Association between 2012 and 2015 were evaluated. The total and per journal proportion of RCTs reporting consent declines was calculated. Percentage of consent declines was also compared based on number of centers and type of setting. Between-groups analysis was done using Chi Square, Chi Square for trend and a Crude odds ratio [95% C.I] were calculated. Results Only 3.7% of the published articles were RCTs. Of the 1103 RCTs, only 532 reported consent declines. JAMA had the highest RCTs reporting consent declines, the Lancet [129,150/781,924, 16.5%] had the most participants declining consent. Difference was significant using Chi square for linear trend [ p < 0.00001]. Consent decline rate was higher in developed countries relative to developing countries [cOR: 2.27, p < 0.000001] and in single centric versus multicentric studies [cOR : 3.63, p < 0.0000001]. Conclusion Both authors and journal editors need to ensure better reporting of consent declines. (shrink)

According to familiar accounts, Rousseau held that humans are actuated by two distinct kinds of self love: amour de soi, a benign concern for one's self-preservation and well-being; and amour-propre, a malign concern to stand above other people, delighting in their despite. I argue that although amour-propre can (and often does) assume this malign form, this is not intrinsic to its character. The first and best rank among men that amour-propre directs us to claim for ourselves is that of occupying (...) 'man's estate'. This does not require, indeed it precludes, subjection of others. Amour-propre does not need suppression or circumscription if we are to live good lives; it rather requires direction to its proper end, not a delusive one. (shrink)

Life, but not as we know it -- Still life in nearly present time -- Driving and the city -- Movement-space -- Afterwords -- From born to made -- Spatialities of feeling -- But malice aforethought -- Turbulent passions.

This paper elaborates on conceptual, empirical and practical arguments why corporations need to focus on their social dimensions, in order to further enhance organizational performance. The paper starts with an introduction on the general trend towards inclusiveness and connectedness. It then elaborates on the phase-wise development of cultures and organizational structures. Managing corporate improvement by building cultures of trust is the central focus of this contribution. By showing the cultural dimensions of Great Places to Work and their workplace practices, worthwhile (...) experiences leading to organizational improvement and superior financial performance are demonstrated. (shrink)

This part of the philosophy of psychology I refer to as 'moral psychology'; and, therefore, this book is offered as a contribution to moral psychology. ...

How do we refer to people in everyday conversation? No matter the language or culture, we must choose from a range of options: full name ('Robert Smith'), reduced name ('Bob'), description ('tall guy'), kin term ('my son') etc. Our choices reflect how we know that person in context, and allow us to take a particular perspective on them. This book brings together a team of leading linguists, sociologists and anthropologists to show that there is more to person reference than meets (...) the eye. Drawing on video-recorded, everyday interactions in nine languages, it examines the fascinating ways in which we exploit person reference for social and cultural purposes, and reveals the underlying principles of person reference across cultures from the Americas to Asia to the South Pacific. Combining rich ethnographic detail with cross-linguistic generalizations, it will be welcomed by researchers and graduate students interested in the relationship between language and culture. (shrink)

"Contemporary Mind - Some Modern Answers" is a fantastic collection of essays by English science writer John W. Sullivan. They deal with a range of subjects, ranging from mysticism and immortality to the relationship between science and art. John William Navin Sullivan (1886 - 1937) was a literary journalist and popular science writer most famous for his study of Beethoven. He is also responsible for having written some of the earliest non-technical accounts of Einstein's General Theory of Relativity, and he (...) was acquainted with many important writers in London in the 1920s, including John Middleton Murry, Aldous Huxley, Wyndham Lewis, Aleister Crowley and T. S. Eliot. Other notable works by this author include "Aspects of Science" (1923), "Aspects of Science: Second Series" (1926), and An Outline of Modern Knowledge (1931). Contents include: "The Balanced Life," "The Problem of Suffering," "The Necessity of Mysticism," "Human Immortality," "A Dissertation on Beethoven," "The Scientific Outlook," "A Dissertation on Maxwell," "New Principles," "A Dissertation on Newton," "Science and Art," "Mathematics and Culture," "Sir Josiah Stamp," "Mr. Aldous Huxley," etc. Many vintage books such as this are increasingly scarce and expensive. It is with this in mind that we are republishing this volume now in an affordable, modern, high-quality edition complete with the original text and artwork. (shrink)

Scientific and technological advances are lending pressure to expand the scope of newborn screening. Whereas this has great potential for improving child health, it also challenges our current perception of such programmes. Standard newborn screening programmes are clearly justified by the fact that early detection and treatment of affected individuals avoids significant morbidity and mortality. However, proposals to expand the scope and complexity of such testing are not all supported by a similar level of evidence for unequivocal benefit. We argue (...) that screening for genetic susceptibility to complex disorders is inherently different from standard screening and, while of potential value, must be considered separately from conventional testing. (shrink)

Bede's Ecclesiastical History is the most important single source for early medieval English history. Without it, we would be able to say very little about the conversion of the English to Christianity, or the nature of England before the Viking Age. Bede wrote for his contemporaries, not for a later audience, and it is only by an examination of the work itself that we can assess how best to approach it as a historical source. N.J. Higham shows, through a close (...) reading of the text, what light the Ecclesiastical History throws on the history of the period and especially on those characters from seventh- and early eighth-century England whom Bede either heroized, such as his own bishop, Acca, and kings Oswald and Edwin, or villainized, most obviously the British king Cædwalla but also Oswiu, Oswald's brother. In (Re-)Reading Bede, N.J. Higham offers a fresh approach to how we should engage with this great work of history. He focuses particularly on Bede's purposes in writing it, its internal structure, the political and social context in which it was composed and the cultural values it betrays, remembering always that our own approach to Bede has been influenced to a very great extent by the various ways in which he has been both used, as a source, and commemorated, as man and saint, across the last 1,300 years. (shrink)

There were five kinds of cyber deterrence presented at the workshop on Landscaping strategic cyber deterrence, hosted at the Oxford Internet Institute. They were the well-studied areas of deterrence by ‘punishment’ and ‘denial’, and the novel concepts of deterrence by ‘association’, ‘norms and taboos’, and finally, ‘entanglement’. In the following workshop commentary, I present these five kinds of deterrence and explain them in light of recent developments in the academy and industry. I argue for analytical congruence between all three novel (...) concepts, since they aim to alter the behaviour of actors by adding a social cost in response to breaking norms and conventions. Throughout, I argue that we are beginning to understand how cyber deterrence works, both in theory and practice, and when all concepts are taken together, they become more than the sum of their parts. Finally, I point out an omission of the workshop, where computational modelling and simulation could be added to the landscape of strategic cyber deterrence. (shrink)

Did Alcidamas invent the story of the contest of Homer and Hesiod? Martin West has argued that he did , 433 ff.). I believe that there are a number of reasons for thinking this improbable. The stories of the deaths of Homer and Hesiod were traditional before Alcidamas. Heraclitus knew the legend of the riddle of the lice and Homer's death , and the story of Hesiod's death was well known by Thucydides’ time . The first attempt to record information (...) about Homer's life is ascribed to Theagenes of Rhegium, in the late sixth century b.c. . By that time it seems likely that there was already a considerable body of legends about the early poets. The pieces of hexameter verse in the Herodotean Life of Homer, some of which show detailed knowledge of the area around Smyrna in the archaic period, probably date from before 500 b.c. In relating the stories of the poets’ deaths Alcidamas is recording the results of στορα, and this is what he implies in Michigan papyrus 2754 . West's theory requires one to assume that he has incorporated with these traditions his own fiction of the contest. This seems to me to go against what we know in general about the activity of sophists such as Alcidamas. Although they were capable of inventing myths , there is no evidence that they created such stories about earlier historical figures, rather than collecting popular legends about them, and using these for their own purposes. It is true that Critias used the evidence of Archilochus’ own poetry to draw conclusions about his life . But this is not the same as inventing a story virtually from scratch. Hesiod's own testimony about his poetic victory , the original starting-point for the legend of the contest with Homer, did not on its own provide a basis from which such inferences could be drawn. It seems more likely that the legend is the product of earlier popular embroidery, at a time when speculation about these early poets’ lives was becoming common. (shrink)

We report two experiments in which participants had to judge the time of occurrence of a stimulus relative to a clock. The experiments were based on the control condition used by Libet, Gleason, Wright, and Pearl [Libet, B., Gleason, C. A., Wright, E. W., & Pearl, D. K. . Time of conscious intention to act in relation to onset of cerebral activities : The unconscious initiation of a freely voluntary act. Brain 106, 623–642] to correct for any bias in the (...) estimation of the time at which an endogenous event, the conscious intention to perform a movement, occurred. Participants’ responses were affected systematically by the sensory modality of the stimulus and by the speed of the clock. Such findings demonstrate the variability in judging the time at which an exogenous event occurs and, by extension, suggest that such variability may also apply to the judging the time of occurrence of endogenous events. The reliability of participants’ estimations of when they formed the conscious intention to perform a movement in Libet et al.’s study is therefore questionable. (shrink)

The Homeric Scholia are not the most obvious source for literary criticism in the modern sense. And yet if one takes the trouble to read through them one will find many valuable observations about poetic technique and poetic qualities. Nowadays we tend to emphasize different aspects from those which preoccupied ancient critics, but that may be a good reason for looking again at what they have to say.

This volume offers the first English language collection of academic essays on the post-Holocaust thought of Jean Améry, a Jewish-Austrian-Belgian essayist, journalist and literary author. Comprehensive in scope and multi-disciplinary in orientation, contributors explore central aspects of Améry's philosophical and ethical position, including dignity, responsibility, resentment, and forgiveness.